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In recent years, oligopeptide-1 has emerged as a standout ingredient in the cosmetics industry. This highly active skincare component has gained significant attention, appearing in numerous high-end formulations. But what exactly makes it so popular and effective?   What is Oligopeptide-1?   Oligopeptide-1, also called as tripeptide-1, is a small molecule composed of three amino acids, designed to mimic the body’s natural signaling peptides. Its unique structure allows it to penetrate deep into the skin and “communicate” with skin cells, activating repair and regeneration mechanisms.     The Key Benefits of Oligopeptide-1   Oligopeptide-1 has become a sought-after ingredient thanks to its wide-ranging skincare benefits:   Boosts Collagen Production As we age, collagen levels in the skin decline, leading to wrinkles and loss of elasticity. Oligopeptide-1 stimulates fibroblasts to produce collagen, helping to firm the skin and reduce fine lines.   Repairs the Skin Barrier It strengthens the skin’s natural barrier, improving resilience and protecting against environmental damage. This makes it especially beneficial for sensitive skin.   Accelerates Skin Healing Mimicking the effects of growth factors, oligopeptide-1 promotes faster cell turnover and repair, making it effective for reducing acne scars and addressing damaged skin.   Antioxidant and Anti-Inflammatory Properties Oligopeptide-1 combats free radical damage while soothing inflammation, helping maintain a calm and healthy complexion.   Why Are More People Choosing Products with Oligopeptide-1 ?   Effective Yet Gentle: Oligopeptide-1 works in harmony with the skin’s natural processes and is non-irritating, making it suitable for all skin types, including sensitive skin.   Backed by Science: Research has demonstrated that oligopeptide-1 significantly increases collagen production and improves skin quality, earning it credibility in the skincare world.     Versatile Benefits: Beyond anti-aging, it addresses multiple skin concerns, offering a comprehensive approach to skincare.     Oligopeptide-1 has become a favorite in the cosmetics industry due to its exceptional anti-aging, repair, and protective properties. It not only helps maintain youthful-looking skin but also addresses a variety of skin concerns. With its versatility and effectiveness, it’s no wonder oligopeptide-1 is celebrated as a powerhouse ingredient. Adding a product with oligopeptide-1 to your skincare routine could be your next step toward healthier, more radiant skin!   If you are interested in our products and want to know more details, please contact judyzhou@drop-bio.com.

  Small-molecule peptides have become a trending ingredient in skincare, often touted for their anti-aging benefits. But do they truly live up to the hype when it comes to reducing wrinkles? Let’s explore the science behind their effectiveness.   What Are Small-Molecule Peptides?   Small-molecule peptides are short chains of 2–10 amino acids with low molecular weight, making them easy to absorb through the skin. Once they penetrate the skin barrier, they act directly on the dermis. Common types include tetrapeptides, hexapeptides, and copper peptides, known for stimulating collagen production, enhancing skin elasticity, and providing antioxidant protection.   How Do They Work Against Wrinkles?   1.Stimulating Collagen Production Collagen loss is a key factor in wrinkle formation. Small-molecule peptides activate fibroblasts, boosting collagen synthesis to improve skin firmness and reduce fine lines and wrinkles.   2.Antioxidant Protection Free radicals can damage skin cells and accelerate aging. Small-molecule peptides have antioxidant properties that neutralize free radicals, reducing oxidative stress from UV exposure and pollution.   3.Relaxing Facial Muscles Some peptides, like hexapeptides, block nerve signals to relax facial muscles, effectively softening expression lines such as crow’s feet and forehead wrinkles.   Is There Scientific Evidence?   Studies show that consistent use of peptide-infused skincare products can visibly improve skin elasticity and smoothness within weeks. For instance, 0.1% tetrapeptide-1(0.1mg/mL DropPet® TR-1P) has a collagen-promoting effect, which has been found to significantly reduce crow’s feet and nasolabial folds. However, the effectiveness depends on factors like peptide concentration, formulation, and absorption. Poorly designed products may fail to deliver the desired results.     How to Choose Skincare with Small-Molecule Peptides?   1.Check the Ingredients: Look for clearly labeled peptides like tetrapeptides, hexapeptides, or copper peptides.   2.Prioritize Concentration: Higher peptide concentrations typically yield better results.   3.Be Consistent: Long-term use, combined with good skincare habits like sun protection and hydration, enhances effectiveness.   Conclusion   Small-molecule peptides show promising results in reducing wrinkles, particularly by stimulating collagen production and combating oxidative stress. While they’re not a “magic cure,” they are a valuable tool for slowing down the signs of aging. With the right product and consistent use, small-molecule peptides could become your go-to ally in the fight against wrinkles.     Your skin is in a race against time—small-molecule peptides might just be the secret to staying ahead!   If you are interested in our products and want to know more details, please contact judyzhou@drop-bio.com.

Surfactants, classified under the “catalysts and various auxiliaries” branch of the fine chemicals industry, are an indispensable part of modern production. Often referred to as the “MSG of the industrial world,” they find applications across virtually all fine chemical sectors, including industrial processes, agriculture, personal care, and new material development.   In recent years, personal care and cleaning products have become two of the most significant global consumer markets. Surfactants are key ingredients in these products and are among the substances that come into frequent contact with the skin. Depending on their hydrophilic-lipophilic balance (HLB) value, surfactants can serve multiple functions, such as cleaning, foaming, emulsifying, wetting, dispersing, and solubilizing.   However, many widely used surfactants, such as alkyl sulfonates and alkyl sulfates, are directly applied to the skin in rinse-off personal care products like shampoos and body washes. These compounds may cause skin irritation and allergic reactions, raising concerns about their safety.   Sophorolipids: A Safer, Eco-Friendly Alternative     Sophorolipids, a class of glycolipid biosurfactants produced by yeast fermentation, have gained attention for their unique properties. They are non-toxic, biodegradable, and environmentally friendly, making them one of the most promising natural surfactants with significant market potential.   Sophorolipids provide multiple benefits, including:   Functional Advantages: Effective at dispersing, wetting, retaining moisture, lubricating, and emulsifying. Mild surfactant properties suitable for sensitive applications. Gentle antibacterial effects, efficiently inhibiting Propionibacterium acnes and Lactobacillus. Anti-inflammatory activity, reducing the release of inflammatory cytokines. Inhibition of lipase activity, preventing the breakdown of sebum into free fatty acids.   Skin Benefits: Stimulates dermal fibroblast metabolism and promotes collagen synthesis. Neutralizes free radicals and inhibits elastase activity, enhancing skin elasticity and repair. Activates macrophages and supports fibrinolytic functions.   Environmental and Safety Features: Heat-resistant and stable across a wide pH range. Safe and non-toxic with no irritation to the skin. Fully biodegradable and environmentally sustainable.   Growing Market Adoption   Due to their exceptional performance and safety profile, sophorolipids have already been adopted by leading international brands in personal care and cosmetic products. These end-use products are now widely available in markets across the EU, the US, Japan, and China.

Adenosine is a common active ingredient in skincare products, valued for its potential anti-aging and skin-repairing properties. Here are some of the key benefits of adenosine for the skin: Adenosine boosts the energy metabolism of skin cells and stimulates collagen production, which helps to smooth fine lines and wrinkles while improving skin elasticity and firmness.It also strengthens the skin barrier, contributing to a smoother and healthier complexion. Adenosine has anti-inflammatory properties that can soothe sensitive skin and reduce redness and irritation caused by inflammation. Adenosine stimulates microcirculation in the skin, improving dullness and making skin look more radiant and healthy. Adenosine is often considered a gentle active ingredient for all skin types, including sensitive skin. Precautions： The concentration of adenosine in skincare products is generally low (0.1%-1%), which is sufficient to be effective without irritating the skin. Adenosine can work synergistically with other anti-aging ingredients (e.g., niacinamide, vitamin C), but avoid using it together with ingredients that may cause irritation (e.g., high concentrations of fruit acids).

Sensitive skin often struggles with redness, irritation, and an impaired skin barrier, making it prone to discomfort and inflammation. Vitamin B12 (cobalamin), has emerged as an ideal ingredient for soothing and restoring sensitive skin due to its unique anti-inflammatory and reparative properties. One of the highlights of Vitamin B12 is its excellent anti-inflammatory effects. Dermatitis symptom scores decreased significantly more on the side treated with VB12 cream than on the side treated with blank cream. By reducing the level of inflammation, Vitamin B12 relieves redness and irritation, providing an immediate soothing effect on damaged skin. In addition, vitamin B12 plays a key role in repairing the skin barrier. It promotes protein synthesis, particularly the production of keratin and collagen, which are essential for maintaining the skin's protective layer. A strengthened barrier not only helps lock in moisture, but also protects against external stimuli, thus making the skin less sensitive. Vitamin B12 also possesses powerful antioxidant properties that neutralize free radicals and reduce oxidative stress caused by environmental factors such as UV rays and pollution. This protective effect further reduces the feeling of skin irritation and supports skin health. There are three different specifications of DropCare® VB12 availabled to customers. Gentle and highly effective, Vitamin B12 brings significant improvement to sensitive skin through its multiple actions of soothing, repairing, and protecting, while enhancing the skin's resilience and comfort.

Mandelic acid is an alpha hydroxy acid (AHA) with a relatively large molecular structure, which means it penetrates the skin more slowly and is therefore considered gentler compared to other acids. Due to its lipophilic nature, mandelic acid is particularly suitable for oily and acne-prone skin. Its oil-regulating effects include the following: 1. Dissolving Oil in Pores: Mandelic acid can penetrate deep into the pores to help dissolve excess sebum, clearing out debris that clogs pores and reducing the formation of blackheads and acne. 2. Regulating Oil Secretion: By removing excess oil from the pores, mandelic acid gradually helps balance oil secretion, leaving the skin less shiny and with a fresher appearance. 3. Gentle Exfoliation: As a mild AHA, mandelic acid promotes the shedding of dead skin cells, making the skin smoother and more radiant. This gentle exfoliation helps prevent clogged pores caused by excess buildup.   In addition, mandelic acid has antibacterial and skin-brightening properties, making it suitable for regular use. When using mandelic acid, it’s recommended to introduce it gradually and always pair it with good sun protection to achieve optimal skincare benefits.

Retinoids are substances that are similar in structure and function to retinol, including: Drugs such as retinoic acid (RA), isotretinoin, adapalene, tazarotene, etc.; Retinol (retinol), retinaldehyde, retinyl palmitate, retinyl propionate, retinyl retinoate, and now the up-and-coming hydroxypinazone retinoate (HPR), among others. These substances can be converted into each other, so that there is a transformation pathway: After the body absorbs retinol, if it can't consume it, it converts it into retinyl palmitate and stores it, and when needed, hydrolyzes the palmitate bond with esterase (the red position in the retinol ester structure diagram on the right is broken), and retinol is released.Retinol is stripped of a hydrogen atom and oxidized to become retinaldehyde, which is an intermediate state. Retinaldehyde is further oxidized, adding an oxygen atom that becomes retinoic acid.Retinoic acid (tretinoin/retinoid) is the actual form of retinoid that enters the nucleus to bind to trans-retinoin reaction elements (RAR/RXR) and initiates the corresponding gene expression. It not only retains the efficacy group of tretinoin, but can directly bind to the receptor; It also covers the irritating groups and improves the physical and chemical stability. Cosmetics containing HPR (Hydroxypinacolone Retinoate)  can be used even on VA-sensitive skin, but note that pregnant women should not use them!        

A quick and easy way to get a healthy wheat-skin tone is to apply a tanning product. When selecting a tanning product, people tend to choose different products based on the degree of color they want to achieve. In fact, the main efficacy substance of most products is dihydroxyacetone(DHA). The dosage of dihydroxyacetone(DHA) added determines the final degree of coloration of the product on the skin. So what's the mechanism of dihydroxyacetone discoloration on the skin? Dihydroxyacetone and proteins in the skin undergo a Malanin reaction, turning the cuticle proteins brown.The specific reaction principle is as follows: Dihydroxyacetone(DHA) does not damage the skin, and is considered a safe skin coloring agent. The color is not removed by simple washing, swimming, or natural perspiration, but it only lasts for 5 to 7 days, as skin cells are continuously being shed. Exfoliation, tape stripping, prolonged water submersion, or heavy sweating can lighten the tan, as these all contribute to rapid dead skin cell pealing. Today, dihydroxyacetone(DHA) is the main active ingredient in virtually all sunless tanning skincare preparations. The above pictures were taken from some subjects in a clinical experiment of DropBio. The coloring was recorded after 3 consecutive times (once a day) of using Instant Tanning Mousse with 10% DropBio@ DHA, and the subsequent fading was continuously recorded. So Dihydroxyacetone(DHA) is a very effective ingredient for self-tanning.  

As we all know, ceramide is a lipid that is similar in structure to the substance that makes up the cuticle of the skin, so it can quickly penetrate the skin and maintain the renewal of the skin's natural protective layer, maintain the balance of natural hydration. When combined with the moisture in the cuticle, it can form a net-like structure to firmly lock the moisture. Ceramide is an important skin-activating ingredient in the cuticle that strengthens the skin barrier, rebuilds cells, and reduces the effects of the external environment by forming effective skin surface barriers.      When Ceramide is added to the damaged skin, the composition of the lipids between the cells is improved and the cells on the surface of the skin become compact and regular again.While the moisture inside the skin is locked in, the outside irritation and bacteria can no longer penetrate the skin's surface, effectively reducing sensitivity and acne formation, so Ceramide is a safe, natural and highly effective skin care ingredient.

In the world of scalp care and dandruff treatment, not all active ingredients are created equal. DropCare® SD (Selenium Disulfide) stands out as a clinically proven, highly effective solution for managing dandruff, seborrheic dermatitis, and associated scalp concerns. With a legacy of efficacy and safety backed by pharmacopoeial standards, it is the ingredient of choice for formulators aiming to create high-performance anti-dandruff products. What is DropCare® SD? DropCare® SD is a premium grade of Selenium Disulfide (SeS₂), a recognized active ingredient with keratolytic, antiseborrheic, antifungal, and antibacterial properties. Its INCI name is Selenium Disulfide, CAS No. 7488-56-4. It works by slowing down the excessive turnover of skin cells on the scalp, reducing scaling, relieving itching, and calming inflammation. Its inclusion in the Chinese Pharmacopoeia 2020 underscores its recognized therapeutic value in improving clinical symptoms and reducing recurrence rates in skin conditions. Proven Efficacy Against Dandruff & Itch Clinical studies demonstrate the superior performance of Selenium Disulfide. In a 28-day consumer trial, a shampoo containing 1% Selenium Disulfide showed remarkable results: 93.3% of subjects reported a significant reduction or complete disappearance of dandruff. 90.0% of subjects noted a marked improvement in scalp itch. Instrumental analysis confirmed visible reduction in flakes and scalp irritation, proving its potent anti-dandruff and anti-itch benefits. Superior to Other Common Actives Comparative medical studies place Selenium Disulfide at the forefront of dandruff-fighting ingredients. After 28 days of use: Selenium Disulfide reduced dandruff by 79.50% – outperforming other common agents. Ketoconazole: 73% reduction Piroctone Olamine (ZPT): 65.05% reduction Salicylic Acid: 70.50% reduction Climbazole: 63.50% reduction This data clearly establishes Selenium Disulfide as one of the most effective choices for scalp flake reduction. Gentle Yet Effective: The Amino Acid-Based Formula Understanding the need for effective yet mild formulations, DropCare® SD can be seamlessly incorporated into gentle systems. Research into an amino acid-based shampoo containing Selenium Disulfide resulted in a product with a skin-friendly pH of approximately 5.5. This mild, weak acidic formulation minimizes hair damage while effectively treating seborrheic dermatitis. Long-term use over 42 days showed a consistent and significant decrease in dandruff severity. Key Benefits & Product Features Multi-Action Efficacy: Combats fungi and bacteria, reduces excess sebum fatty acids, and provides anti-inflammatory action. Broad Application: Clinically valuable for treating scalp psoriasis, seborrheic dermatitis, tinea versicolor, and acne. High Patient Compliance: Easy-to-use format in wash-off products promotes regular use and better treatment outcomes. Synergistic Potential: Can be used in combination with oral medications to reduce overall treatment time and relapse rates. Formulation Versatility: Suitable for development into various product forms, enabling innovation in the dandruff care market. Conclusion DropCare® SD (Selenium Disulfide) is more than just a dandruff ingredient; it is a versatile, potent, and trusted active with strong clinical credentials. Its proven superiority over other agents, combined with its adaptability into modern, gentle formulations like amino acid bases, makes it an exceptional choice for brands seeking to develop next-generation scalp care products that deliver visible, soothing results. Choose DropCare® SD for formulations that offer exceptional efficacy, patient acceptance, and a clear competitive edge in the anti-dandruff market. Please contact: judyzhou@drop-bio.com

In the world of modern cosmetics, formulators constantly seek ingredients that are not only effective but also multifunctional, stable, and skin-friendly. Enter DropCare® HL-75 & HL-80(Hydrogenated Lecithin)—a high-purity powdered emulsifier that is redefining texture, delivery, and barrier support in skincare formulations. Available in two grades, HL-80 (≥80% purity) and HL-75 (≥75% purity), this ingredient is engineered for performance and versatility.   What is DropCare® HL-75 & HL-80 ? Derived from natural lecithin and through hydrogenation for enhanced stability, DropCare® HL-80/75 is a finely powdered, high-purity ingredient. CAS No.: 92128-87-5 Appearance: White to off-white powder (HL-80) / White to yellowish powder (HL-75) Specification: 1 kg/bag, 15 kg/barrel It acts as both an emulsifier and an active functional component, making it a valuable addition to a wide array of products—from lightweight serums to rich anti-aging creams.   Why Choose DropCare® HL-75 & HL-80?   1. Superior Emulsification & Texture Enhancement DropCare® HL-80/75 excels at forming stable oil-in-water (O/W) or water-in-oil (W/O) emulsions. Its gentle emulsifying action helps create a luxuriously stable, creamy texture without a greasy after-feel. Whether you’re developing a lotion, cream, or serum, it delivers smooth, spreadable consistency that consumers love. 2. Boosts Active Ingredient Penetration One of its standout features is its role as a penetration enhancer. By improving the skin’s absorption of key actives—such as peptides, vitamins, and antioxidants—it ensures that your formulations deliver visible, effective results. 3. Strengthens the Skin Barrier Beyond emulsification, this hydrogenated lecithin actively supports skin barrier repair and hydration. It helps reinforce the skin’s natural protective layer, making it ideal for moisturizers, barrier creams, and products designed for sensitive or compromised skin. 4. High Stability & Compatibility Thanks to its hydrogenated form, DropCare® HL-80/75 offers exceptional oxidative stability, extending the shelf life of your products. It integrates seamlessly into various systems and is suitable for: Anti-aging creams Moisturizers Sunscreens Lipsticks Cleansing products   How to Use It Recommended Dosage: 0.5% – 5.0% Solubility: Easily soluble in oils (add to the oil phase at 60–80°C). It can also be dispersed in water.⚠️ Note: Control heating time and temperature carefully to avoid discoloration. Storage: Keep in a sealed container below 20°C, protected from light. Shelf Life: 2 years We also offer customized formulation support and can provide sample recipes to help you get started.   Who Is It For? Cosmetic chemists, R&D specialists, and brands looking for a reliable, multifunctional powdered emulsifier that delivers on: Texture refinement Enhanced efficacy of actives Skin barrier health Product stability Whether you are creating the next generation of anti-aging treatments, daily moisturizers, or specialized sunscreen formulas, DropCare® HL-80/75 offers the functional versatility your formulation needs.   Ready to Formulate with DropCare®? Minimum order quantity is flexible (typically starting from 15 kg), and our team is ready to assist you with technical inquiries, samples, or formulation advice. Contact us today to learn more about how DropCare® HL-80 and HL-75 can elevate your product line. Please contact: judyzhou@drop-bio.com

In the evolving world of cosmetic science, the shift towards natural, effective, and sustainable ingredients is stronger than ever. Enter DropCare® CON C3—a premium activated charcoal powder derived from coconut shells, designed to meet the highest standards of performance, safety, and environmental responsibility. This innovative material is not just another additive; it’s a versatile powerhouse capable of enhancing a wide range of personal care products. What is DropCare® CON C3? DropCare® CON C3 is a high-performance activated carbon material sourced from high-quality coconut shells.INCI Name: Charcoal PowderCAS No.: 16291-96-6 It belongs to the efficacy categories of oil adsorption, gentle exfoliation, deep cleansing, and natural tinting. Why Choose DropCare® CON C3? ✅ 100% Natural & Renewable Made exclusively from coconut shells, it is a fully renewable, biodegradable, and eco-friendly material. It serves as an excellent sustainable alternative to synthetic microbeads and plastic exfoliants. ✅ Highly Porous Structure Its developed pore system and enormous specific surface area provide a strong physical foundation for superior adsorption capabilities—capable of adsorbing 100–200 times its own weight. ✅ Strong Adsorption & Fast Action Efficiently absorbs excess sebum, impurities, pollutants, and microscopic particles from skin and hair, promoting a deeply cleansed and refreshed feel. ✅ Gentle Yet Effective Exfoliation With controlled particle size and rounded edges, it offers adjustable physical exfoliation, gently removing dead skin cells without causing irritation—perfect for sensitive skin formulations. ✅ High Safety & Non-Toxic Free from polycyclic aromatic hydrocarbons, heavy metals, and impurities. Non-irritating, non-comedogenic, and clinically tested for safety in cosmetic applications. Technical Specifications (DropCare® CON C3)     Parameter Specification Appearance Black Powder Odor Odorless Loss on Drying, % ≤ 12.0 Adsorption Capacity (Iodine), % ≥ 95.0 Ash Content, % ≤ 4.00 pH Value 8.0–11.0 Heavy Metals (As, Pb, Cd, Hg) Meets strict limits Microbial Count < 100 CFU/g Multifunctional Applications in Cosmetics 1. Deep Cleansing & Purification Acts like a “magnet” to physically adsorb excess oil, dirt, and pollutants from skin and scalp.Ideal for: Facial cleansers, cleansing powders, detox masks, shower gels, and clarifying shampoos. 2. Gentle Exfoliation & Skin Refinement Provides controllable physical exfoliation to smooth and renew skin texture.A natural alternative to plastic microbeads, aligned with global “microplastic-free” trends.Used in: Facial/body scrubs, polishing masks. 3. Oil Control & Pore Management Helps reduce surface shine and keep pores clear with long-term use.Suitable for: Oil-control cleansers, mattifying serums, primers, T-zone treatments, and scalp care shampoos. 4. Oral Care & Whitening Physical Polishing: Gently removes extrinsic stains from coffee, tea, or smoking without damaging enamel. Adsorptive Freshness: Helps adsorb odor-causing compounds for long-lasting freshness.A great complement or alternative to silica in: Toothpaste and tooth powders. 5. Active Ingredient Carrier Its porous structure acts as a “micro-container” to encapsulate and deliver active ingredients (e.g., vitamins, extracts) for enhanced efficacy and sustained release. 6. Product Texture & Stabilization Helps suspend particles evenly in formulations, prevent settling, and adds a unique visual identity (e.g., “black paste” concepts).Perfect for: Suspension serums, two-phase masks, men’s black series, and trendy charcoal toothpaste. Usage Guidelines Recommended Inclusion: 0.5% – 5% Solubility: Insoluble in water, disperses well in various systems. Storage: Store at room temperature, avoid high heat and humidity. Shelf Life: 2 years. Embrace Natural Performance DropCare® CON C3 is more than an ingredient—it’s a commitment to cleaner, smarter, and greener cosmetic science. Whether you’re formulating the next-generation cleanser, a gentle exfoliator, a mattifying skincare line, or an innovative oral care product, this natural activated charcoal delivers outstanding functionality without compromising on safety or sustainability. Drop(Nanjing) Bio-Tech Co., Ltd.Little by little, Make the Future.📍 Nanjing, China📧 Contact us for samples, technical data, and formulation support. Please contact: judyzhou@drop-bio.com