skinceuticals phloretin

In the ever-evolving world of skincare, consumers are increasingly seeking natural, effective, and safe ingredients. Meet DropBrigt® Phlor—a powerful plant-derived active that is revolutionizing cosmetic formulations with its exceptional multi-functional benefits. What is Phloretin? Phloretin is a natural dihydrochalcone flavonoid predominantly found in the peel and root bark of apples, pears, and other succulent fruits, as well as in plants like sweet tea and crabapple. Known for its strong antioxidant properties, phloretin has become a star ingredient in both cosmetics and functional foods. INCI Name: Phloretin CAS No.: 60-82-8 Molecular Formula: C₁₅H₁₄O₅ Key Benefits in Cosmetics 🌟 Skin Brightening & Whitening Phloretin effectively inhibits melanocyte activity and reduces the appearance of skin pigmentation and spots. Studies show that it outperforms well-known brightening agents like kojic acid and arbutin in tyrosinase inhibition. When combined with these agents, phloretin can achieve up to 100% inhibition—without the side effects. ✨ Antioxidant & Anti-Aging With an antioxidant capacity of 10.30 mg/L for lipid oxidation, phloretin neutralizes free radicals such as DPPH and ABTS, protects mitochondrial integrity, and delays skin aging. It helps maintain skin youthfulness and resilience against environmental stressors. 🔁 Anti-Inflammatory & Acne Care Phloretin soothes inflamed skin by blocking sugar penetration into epidermal cells, regulating sebum production, reducing COX-2 promoter activity, and inhibiting prostaglandin E2 synthesis. This makes it ideal for acne treatments and sensitive skin formulations. 💧 Transdermal Enhancement A safe and effective penetration enhancer, phloretin improves the absorption of other functional ingredients within cosmetic formulations, maximizing their efficacy—e.g., it significantly boosts the percutaneous absorption of Lidocaine HCl. 💆 Hair Loss Prevention By inhibiting soybean lipoxygenase (LOX), phloretin helps prevent premature hair aging and loss, making it a valuable addition to hair care products. Applications in Cosmetics Phloretin is widely used in a variety of skincare products, including: Whitening creams Repair serums Essences and toners Anti-aging treatments Acne solutions and soothing products Hair growth serums Leading global brands like SkinCeuticals have already incorporated phloretin into their bestselling products, recognizing its potent efficacy and consumer appeal. Safety & Regulations Phloretin is not only highly effective but also extremely safe: Oral LD₅₀: 5.760 g/kg (very low toxicity) Approved for use in cosmetics under China cosmetic ingredient code 02548 Complies with food additive standards (GB 1886.261-2016, GB2760 #N376) Recognized as GRAS by FEMA (#A390) and JECFA (#2022) Technical Specifications Indicator Specification Appearance Pearly white to light pink/yellow powder Odor Characteristic Assay ≥95.0% Melting Point 260–262°C Heavy Metals (Pb) ≤10 ppm Total Plate Count <1000 CFU/g Beyond Cosmetics: Food & Flavor Applications Phloretin also serves as a natural flavor modifier—especially useful in sugar-free or low-sugar food and beverage products. It masks bitterness, reduces off-notes from high-intensity sweeteners, and improves overall taste perception, often used in combination with stevia. Conclusion DropBrigt® Phlor is a versatile, evidence-based, and naturally derived active ingredient that meets the growing demand for safe and multifunctional components in cosmetics. Whether you’re developing serums, creams, toners, or haircare products, phloretin offers a compelling blend of efficacy, safety, and consumer trust. Enhance your formulations with DropBrigt® Phlor—where nature meets science. If you are interested in our products and want to know more details, please contact judyzhou@drop-bio.com.