Carnosine antioxidant

In the ever-evolving world of skincare ingredients, one bioactive peptide stands out for its remarkable dual-protective capabilities: Carnosine. Marketed as DropPet® LC , this high-purity, water-soluble dipeptide is revolutionizing formulations aimed at combating visible signs of aging. Let's delve into why this ingredient is becoming a staple in advanced cosmetic science. What is DropPet® LC ? Carnosine (β-Alanyl-L-histidine) is a naturally occurring dipeptide found in high concentrations in human muscle and brain tissues. Our DropPet® LC is a synthetic, bio-identical version of this molecule, offering exceptional purity and stability for cosmetic applications. With the INCI name Carnosine (CAS 305-84-0), it is a versatile and potent active for modern skincare.   Core Benefits: A Shield Against Aging DropPet® LC  provides a two-fold defensive strategy for the skin: Potent Antioxidant Activity: It effectively scavenges harmful free radicals like Reactive Oxygen Species (ROS) and α,β-unsaturated aldehydes generated by UV exposure and pollution. This action protects cellular proteins and lipids from oxidative stress, a key driver of premature aging and photo-damage. Advanced Anti-Glycation Action: Carnosine acts as a "carbonyl scavenger," inhibiting the formation of Advanced Glycation End-products (AGEs). AGEs damage collagen and elastin, leading to loss of firmness, wrinkles, and a dull complexion. By protecting proteins from sugar-induced damage, carnosine helps maintain skin's youthful structure and radiance.   Proven by Science: Efficacy Data Our extensive research validates the power of DropPet® LC: Superior Free Radical Scavenging: In DPPH assays, Carnosine shows significantly higher free radical scavenging activity (up to 53.1% at 100 mmol/L) compared to its individual amino acid components, L-Alanine and L-Histidine. pH & Temperature Stability: It maintains high efficacy across a broad pH range (optimal in mildly acidic conditions) and exhibits excellent thermal stability, withstanding high temperatures (up to 100°C for 15 minutes) without significant loss of activity, making it suitable for various manufacturing processes. Cellular & ECM Benefits: Studies using 3D human dermal spheroid models indicate that Carnosine supports healthy extracellular matrix (ECM) reorganization and helps combat cellular senescence, contributing to skin firmness and resilience. Anti-Apoptotic Protection: Research published in Progress in Modern Biomedicine demonstrates Carnosine's ability to protect cells from high glucose-induced oxidative stress and apoptosis by downregulating key caspase proteins, highlighting its protective mechanism at the cellular level.   Key Product Advantages Water-soluble & Easy-to-Use: Simplifies formulation into a wide range of skincare products. Broad-Spectrum Application: Ideal for anti-aging, brightening, antioxidant, anti-glycation, and anti-photoaging formulations. Exceptional Stability: Stable at pH 3.0–7.0 and heat tolerant. Metal Chelation: Offers mild chelating activity against Fe²⁺ and Cu²⁺ ions, which can catalyze oxidative reactions.   Technical Specifications & Safety DropPet® LC meets rigorous quality standards: Item Specification Appearance Off-white to white powder Assay (HPLC) 99.0 – 101.0 % Loss on Drying ≤ 1.0% pH (1% Solution) 7.0 – 9.0 Heavy Metals ≤ 10 ppm Total Plate Count ≤ 1000 cfu/g E. Coli / Salmonella Negative   Application Guidance Solubility: Highly water-soluble. Recommended Dosage: 0.1% to 2.0%. Applications: Perfect for serums, creams, lotions, eye care, and ampoules targeting firming, brightening, and overall anti-aging benefits. Market Presence: This trusted ingredient is already featured in products from renowned brands like La Roche-Posay, Proya, Dr.Ci:Labo, HomeFacialPro, Shiseido, and Olay.   Conclusion DropPet® LC is more than just an antioxidant; it's a comprehensive anti-aging agent that addresses both oxidation and glycation—two fundamental pathways of skin aging. Its proven efficacy, outstanding stability, and formulation flexibility make it an essential ingredient for creating next-generation skincare that truly delivers on the promise of preserved youth and vitality.     Ready to integrate this dual-action powerhouse into your formulations? Contact us to request a sample or technical dossier of DropPet® LC. Please contact: judyzhou@drop-bio.com