Phloretin Cosmetic Ingredients

In the quest for high-performance, multifunctional, and naturally-derived ingredients, the cosmetic and nutraceutical industries are constantly evolving. At the forefront of this innovation is DropBright® Phlor, a potent bioactive compound that bridges the gap between skincare science and holistic wellness. Sourced naturally from apple and pear tree bark, this remarkable ingredient from DropBio is redefining standards for efficacy and safety. What is DropBright® Phlor? DropBright® Phlor is a premium grade of Phloretin, a dihydrochalcone flavonoid known for its powerful antioxidant properties. With the INCI name Phloretin and CAS No. 60-82-2, it is a versatile molecule (C15H14O5) celebrated for its multi-targeted benefits. Recognized as safe by major global authorities—including China's cosmetic ingredient directory (No. 02548), JECFA, and FEMA GRAS (#4390)—its excellent safety profile is underscored by an extremely low oral toxicity (LD50 >5g/kg). A Multifaceted Powerhouse for Skin Health DropBright® Phlor's mechanism of action is as diverse as its benefits, making it a star ingredient in serums, creams, ampoules, and essences. Superior Skin Brightening & WhiteningDropBright®Phlor is a champion for achieving a radiant, even-toned complexion. It effectively inhibits tyrosinase activity—the key enzyme in melanin production—more potently than conventional agents like kojic acid and arbutin. Studies show that at 10 µg/mL, DropBright® Phlor achieves a 69.88% inhibition rate. When combined with other brighteners, it can work synergistically for enhanced results without the associated irritancy of some synthetic alternatives. Potent Antioxidant & Anti-Aging DefenderAs a robust antioxidant, DropBright® Phlor neutralizes free radicals generated by UV exposure and pollution. It protects skin lipids from peroxidation and helps preserve mitochondrial function in cells, which is crucial for cellular energy and longevity. By combating oxidative stress, it visibly reduces fine lines, wrinkles, and other signs of premature aging. Effective Anti-Inflammatory & Soothing AgentSkin inflammation is at the root of many concerns, from sensitivity and redness to acne. DropBright® Phlor demonstrates significant anti-inflammatory properties, helping to calm skin, reduce irritation, and alleviate conditions like atopic dermatitis. It works by inhibiting inflammatory pathways and mediators like histamine. Remarkable Penetration EnhancerUniquely, DropBright® Phlor acts as a safe and effective transdermal penetration booster. It improves the skin's absorption of other valuable actives in a formulation—such as Vitamin C, peptides, or lidocaine—ensuring they reach deeper layers where they are most effective, thereby maximizing the performance of the entire product. Hair Care Benefits: Combating Hair LossEmerging research highlights DropBright® Phlor's role in scalp health. It helps inhibit follicular cell apoptosis (programmed cell death) by modulating specific inflammatory pathways (NF-κB), potentially improving hair density and reducing hair loss. Beyond Beauty: Holistic Wellness Applications DropBright® Phlor's benefits extend far beyond topical application, showcasing significant potential in the nutraceutical and functional food space. Internal Antioxidant & Anti-Aging: Supports cellular health from within. Liver Protection: Shown to offer protective effects against chemical-induced liver damage. Anxiety Relief & Mood Support: Studies indicate an anti-anxiety effect by modulating stress responses. Functional Food & Beverage: Used in dietary supplements, solid drinks, and health beverages for immune support, metabolism promotion, and overall wellness. It also serves as a natural flavor modifier, perfect for masking bitterness in "zero-sugar" or low-sugar products. Trusted by Brands, Backed by Science DropBright® Phlor is no longer a niche ingredient. It has been adopted by leading skincare brands worldwide, most notably as a star component in SkinCeuticals' (L'Oréal) acclaimed formulations. Its presence in high-end serums and creams validates its prestige and proven results in the market. Seamless Integration into Formulations DropBright® Phlor is a highly stable, off-white to light yellow powder with a purity of ≥95%. It is recommended for use at 0.1–2.0% in cosmetic formulations. For optimal stability, store in a cool, dry place, protected from light. Sample Application: 2% DropBright® Phlor Booster SerumThis simple yet powerful formulation showcases how to incorporate DropBright® Phlor with other antioxidants like Vitamin C and Ferulic Acid for a synergistic effect. The Future is Rooted in Nature DropBright® Phlor stands as a testament to the power of botanicals harnessed through science. It offers a rare combination of proven cosmetic efficacy and internal health benefits, all within a framework of outstanding safety. For formulators and brands looking to create the next generation of multifunctional beauty and wellness products, DropBright® Phlor is an indispensable ingredient. It’s not just about treating the skin's surface; it’s about promoting holistic radiance from the inside out. Discover the power of purity. Discover DropBright® Phlor. Please contact: judyzhou@drop-bio.com