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  • Unlock Fuller, Younger-Looking Lips with DropPet® LipS & LipS Hot Oct 24, 2025
    In the world of beauty, the quest for a perfect, plump pout is never-ending. Consumers are increasingly seeking solutions that go beyond temporary hydration, looking for ingredients that offer tangible, long-term benefits. Meet DropPet® LipS and DropPet® LipS Hot – our innovative, peptide-powered raw materials designed to revolutionize your lip care formulations. The Science of a Perfect Pout At the heart of both products is the powerful signaling peptide, Palmitoyl Tripeptide-1 (Pal-GHK). This renowned peptide is a game-changer for skin rejuvenation. Here’s how it works: Stimulates Collagen Synthesis: Palmitoyl Tripeptide-1 acts on the TGF-β receptor, stimulating fibroblast proliferation. This, in turn, boosts the production of key structural proteins like Type I and Type III collagen, elastin, laminin, and fibronectin. Increases Skin Thickness: By strengthening the dermal structure, it helps to increase skin thickness and firmness, combating the thinning that occurs with age. Promotes Tissue Renewal: It accelerates wound recovery and tissue reconstruction, leading to healthier, more resilient lip skin. Proven In Vivo Efficacy:A clinical study involving 23 volunteers demonstrated that a cream with just 4 ppm of Pal-GHK significantly increased skin thickness by approximately 4% after 4 weeks. This is a remarkable result, considering skin thins at a rate of about 6% per decade. Two Powerful Formulas, One Core Benefit We offer two variants to suit different formulation needs and desired user experiences: DropPet® LipS (0.1% & 0.01%) The Foundation: A highly effective, oil-soluble ointment raw material specifically designed for lip care. Primary Efficacy: Reduces lip lines, fades cheilogramma (lip discoloration), and improves overall lip health and softness. DropPet® LipS Hot (0.1% & 0.01%) The Enhanced Experience: This variant contains all the benefits of DropPet® LipS, with an added innovative ingredient: Vanillyl Butyl Ether. Instant Sensation: This natural thermal agent provides a warm, tingling sensation upon application, promoting blood circulation for an immediate "plumping" effect. It offers a superior heating experience compared to capsaicin without the risk of burning, delivering comfort and pleasure that consumers love. Compelling Evidence: See the Difference Our in-house in vivo test confirms the powerful lip enhancement effect. Volunteers applied a lip balm containing 0.5% DropPet® LipS (0.1%) three to four times daily. The self-evaluation results were outstanding: Improved Lip Shape: +100% Lip Protection: +70% Lip Softness: +80% High-definition photographic evidence clearly shows visible improvement in lip fullness and a reduction in fine lines after 28 days of use. In Vitro Protection:Beyond aesthetics, Palmitoyl Tripeptide-1 offers protection. Studies show it can prevent collagen degradation in skin samples exposed to UVA light, demonstrating its role in preserving the lip's structural integrity against environmental damage. Formulate with Confidence Application: Perfect for lip creams, balms, masks, and all lip care products. Recommended Dosage: 0.5% - 5.0% Solubility: Oil-soluble. Usage: For best results, add in the final stage of your oil phase, heating to 70-80°C. Quality You Can Trust Both products are available in two concentrations (0.1% and 0.01%) and meet rigorous quality specifications, including low microbial limits and a stable, white to milky paste appearance. They should be stored in a cool, dark place (2-8°C ideal) and have a shelf life of 2 years. Ready to create lip products that deliver visible results and a luxurious experience? Integrate DropPet® LipS or LipS Hot into your next formulation and give your customers the fuller, smoother, and healthier lips they desire. If you are interested in our products and want to know more details, please contact judyzhou@drop-bio.com.  
  • DropCare® EDDS: The Next-Generation, Eco-Conscious Chelator for Modern Cosmetics Oct 14, 2025
    In the evolving world of cosmetic science, the demand for high-performance, safe, and sustainable ingredients has never been greater. Meet DropCare® EDDS (Trisodium Ethylenediamine Disuccinate), a groundbreaking green chelator that is setting a new standard for efficacy and environmental responsibility in personal care formulations.   What is DropCare® EDDS? DropCare® EDDS is a phosphorus-free, readily biodegradable chelating agent. Its molecular structure, derived from ethylenediamine and succinic acid, contains multiple coordination atoms that form highly stable complexes with metal ions. This makes it a powerful and versatile ingredient for a wide range of cosmetic and personal care applications.   Key Identifiers: INCI Name: Trisodium Ethylenediamine Disuccinate CAS No.: 9001-73-4   Why Choose EDDS Over Traditional Chelators? Compared to conventional chelators like EDTA, DropCare® EDDS offers significant advantages in selectivity, safety, and sustainability: Superior Metal Ion Selectivity: EDDS exhibits a high affinity for transition metal ions like copper and iron, which are primary catalysts for oxidation in formulations. It has a weaker effect on calcium and magnesium, thereby reducing the risk of corrosion to equipment and irritation to the skin. Excellent Biodegradability: This is its standout feature. While traditional chelators can persist in the environment, EDDS is rapidly and completely broken down by microorganisms. Studies show it can achieve full mineralization in soil within 28 days, with a half-life of just 2.5 days. This aligns perfectly with global "Clean Beauty" trends and stringent EU and China regulations for eco-friendly ingredients. High Performance in Formulations: It is stable under high temperatures and in a broad pH range (recommended use between pH 3-9), making it suitable for diverse product types.   Key Functions & Benefits in Cosmetic Formulations 1. Stabilizes Formulations by Chelating Metal IonsMetal ions in water or raw materials can cause product instability, leading to cloudiness, precipitation, or reduced efficacy of surfactants. DropCare® EDDS effectively sequesters these ions (e.g., Fe, Cu, Al), ensuring the clarity, stability, and performance of cleansers, shampoos, and other rinse-off products, even in hard water conditions. 2. Enhances Antioxidant & Preservation EfficacyMetal ions accelerate the oxidation of oils, fragrances, and active ingredients like Vitamin C. By chelating these pro-oxidant metals, EDDS acts as an indirect antioxidant, prolonging product shelf life and protecting the integrity of valuable actives. It also works synergistically with preservatives like phenoxyethanol, allowing for potential reduction in preservative concentrations while maintaining antimicrobial efficacy. 3. Regulates pH & Reduces IrritationAs a weakly acidic substance, DropCare® EDDS helps buffer formulations to a pH level closer to the skin's natural acidic mantle (pH 5.5-6.0). This helps minimize potential skin irritation, enhancing product mildness and comfort. 4. Maintains Charge Balance & ViscosityIn formulations thickened with inorganic salts, metal ions can disrupt charge balance, leading to viscosity changes and instability. EDDS helps maintain ionic equilibrium, ensuring consistent product texture and performance.   Technical Profile   Items Specification Appearance White powder pH (as is) 2.0 - 5.0 Assay, % ≥ 98.0 Residue on Ignition, % ≤ 0.5 Heavy Metal (as Pb), ppm ≤ 10 Total Plate Count, CFU/g ≤ 1000 Yeast & Mould, CFU/g ≤ 100   Application Guidance Recommended Use Level: 0.1% - 3.0% (A typical usage range is 0.6% - 1.3%). Solubility: Excellent water solubility. Recommended For: Shampoos & Conditioners Soaps & Body Washes Creams & Lotions Sun Care Products Storage: Store in a cool, dry, and dark place in a sealed container. For optimal stability, storage at 2-8°C is recommended. Shelf life is 2 years.   A Note on Compatibility: Avoid combining with extreme pH ingredients, strong oxidizers/reducing agents, or other chelators. For sensitive skin products, consider using at concentrations ≤ 0.1%.   Conclusion DropCare® EDDS is more than just a chelator; it's a strategic choice for brands committed to creating high-performance, safe, and environmentally sustainable cosmetics. Its powerful chelation, combined with its rapid biodegradability, makes it the ideal ingredient for the future of clean and effective beauty. Embrace the future of green formulation. Formulate with DropCare® EDDS. If you are interested in our products and want to know more details, please contact judyzhou@drop-bio.com.  
  • DropCare® DO: The Science-Backed Solution for Healthier, Stronger Hair Sep 30, 2025
    In the world of hair care, combating hair loss and promoting robust hair growth requires innovative, scientifically formulated ingredients. DropCare® DO (Diaminopyrimidine Oxide) is a cutting-edge active ingredient designed to address the root causes of hair thinning and loss, making it an ideal choice for modern hair care formulations. What is DropCare® DO? DropCare® DO is a powerful hair care active with the INCI name Diaminopyrimidine Oxide. It is specifically developed to: Inhibit hair loss Promote hair growth By targeting key biological processes within the hair follicle, DropCare® DO helps restore hair vitality and support continuous healthy growth. How Does DropCare® DO Work? Hair loss, particularly androgenetic alopecia (AGA), is often driven by hormonal factors and oxidative stress, leading to follicle miniaturization and fibrosis. DropCare® DO acts through a dual mechanism: Inhibition of 5α-ReductaseDropCare® DO reduces the conversion of testosterone to dihydrotestosterone (DHT), a key hormone responsible for follicle shrinkage and hair thinning in AGA. Anti-Fibrotic ActionBy inhibiting lysyl hydroxylase—an enzyme involved in collagen maturation—DropCare® DO helps soften hardened collagen around hair follicles. This reduces fibrosis, improves nutrient supply to the hair bulb, and prevents premature hair root degradation. Why Choose DropCare® DO Over Traditional Treatments? While treatments like minoxidil are commonly used, they often come with side effects such as skin irritation, allergic reactions, and restrictions for cosmetic use. DropCare® DO offers a safer, cosmetic-friendly alternative with proven efficacy and minimal risk of adverse effects. Key Benefits at a Glance ✅ Reduces DHT production by inhibiting 5α-reductase ✅ Softens collagen deposits around follicles to prevent hardening ✅ Revitalizes hair roots and extends the hair growth cycle ✅ Suitable for use in anti-hair loss and lash-enhancing products ✅ Safe, soluble, and stable in cosmetic formulations Application & Formulation Guidance Recommended Use: Anti-hair loss, hair strengthening, and eyelash growth formulations Recommended Inclusion: 0.5–1.5% Solubility: Compatible with water, 1,2-propanediol, 1,3-butanediol, and 1,2-pentanediol Stability: Optimal at pH ~5.5; may precipitate outside this range at concentrations >1.5% Product Specifications     Parameter Specification Appearance White to off-white powder Odor Characteristic Water (KF) 12–14% Turbidity < 10 FNU Purity (HPLC) ≥ 98.0% Conclusion DropCare® DO represents a new generation of hair actives—rooted in science, designed for performance, and safe for daily use. Whether you're developing a serum, shampoo, or conditioner, this ingredient offers a reliable and effective solution for consumers seeking to restore and maintain healthy hair. Ideal for: Anti-hair loss shampoos & treatments Eyelash growth serums Scalp care and revitalizing products Formulate with Confidence. Formulate with DropCare® DO. If you are interested in our products and want to know more details, please contact judyzhou@drop-bio.com.  
  • Unlock Age-Defying Skin: Discover the Power of DropPet® M3000 Sep 29, 2025
    In the relentless pursuit of youthful, firm, and radiant skin, cosmetic chemists are constantly seeking high-performance active ingredients that deliver visible, proven results. Meet DropPet® M3000, a powerful synergistic blend of two renowned peptides designed to fight wrinkles at their source and recreate the stereoscopic contours of the face. A Synergistic Powerhouse of Peptides At the heart of DropPet® M3000 lies a precise combination of two bio-mimetic peptides: Palmitoyl Tripeptide-1 (Pal-GHK): A cellular communicator known for its ability to stimulate the synthesis of key matrix macromolecules like collagen and glycosaminoglycans, effectively targeting and reducing the appearance of wrinkles. Palmitoyl Tetrapeptide-7 (Pal-GQPR): Works as an anti-inflammatory cellular messenger to support the skin's natural recovery process, stimulating collagen regeneration in the dermis and helping to restore a firmer, more resilient skin structure. Together, this dynamic duo works in harmony to provide a comprehensive anti-aging solution. Key Efficacy & Skin Benefits DropPet® M3000 offers a multi-faceted approach to skin rejuvenation: Firming & Renewal: Visibly tightens the skin and helps restore its youthful, three-dimensional contours. Boosts Matrix Synthesis: Promotes the skin's natural production of essential macromolecules—elastin, collagen, and hyaluronic acid. Increases Skin Thickness & Elasticity: By reinforcing the dermal structure, it leads to thicker, more supple, and resilient skin. Repairs the Skin Barrier: Strengthens the skin's natural defense system for healthier-looking skin. Deep Hydration: Helps increase the skin's hyaluronic acid content, attracting and binding moisture to the epidermis for a plumper, dewier complexion. Proven Clinical Results: See the Difference Data speaks louder than words. In a clinical study, 30 female volunteers aged 30-60 applied a cream containing 5% DropPet® M3000 to one side of their face (around the eyes and cheeks) for 8 weeks. The results, measured using the PRIMOS Lite system for precise wrinkle volume analysis, were significant: After 2 Weeks: A 15.7% improvement in total wrinkle volume. After 4 Weeks: A 21.7% improvement in total wrinkle volume. After 8 Weeks: A remarkable 30.2% reduction in total wrinkle volume. Statistical analysis confirmed that the improvement in the test group was significantly greater than in the control group (P < 0.05), validating the potent anti-wrinkle efficacy of DropPet® M3000. [Image: A graph showing the decreasing trend of wrinkle volume (ΔV) in the test group over 8 weeks.] Technical Profile & Application DropPet® M3000 is a versatile and stable ingredient, formulated for easy integration into your next high-performance skincare product. INCI Name: PALMITOYL TRIPEPTIDE-1 & PALMITOYL TETRAPEPTIDE-7 Appearance: Semitransparent viscous liquid Recommended Dosage: 3-5% Solubility: Disperses well in water (translucent solution). Ideal For: Anti-aging serums, creams, lotions, and high-end rejuvenating products. Storage: For optimal stability, store sealed in a cool place (2-8°C is best), protected from light. With its proven efficacy and compatibility, it's an ingredient worthy of brands like Elizabeth Arden, La Prairie, and CLINIQUE. Conclusion DropPet® M3000 is more than just a peptide blend; it's a scientifically-backed solution for significant skin rejuvenation. By effectively promoting the skin's natural repair and regeneration processes, it delivers on the promise of firmer, smoother, and more youthful-looking skin.   Ready to formulate the next generation of anti-aging cosmetics? Contact us today to learn more about incorporating DropPet® M3000 into your product line. If you are interested in our products and want to know more details, please contact judyzhou@drop-bio.com.
  • Enhance and Revitalize: Discover DropPet® LipS & LipS Hot for Beautiful, Fuller Lips Sep 25, 2025
    When it comes to lip care, consumers are looking for more than just hydration—they want visible results. That’s where DropPet® LipS (0.1%) and DropPet® LipS Hot (0.1%) come in. These innovative, peptide-based raw materials are specially formulated to address common lip concerns such as fine lines, loss of firmness, and uneven tone, while delivering a noticeable plumping effect. What Are DropPet® LipS and LipS Hot? Both products are ointment-style ingredients containing Palmitoyl Tripeptide-1, a well-studied signaling peptide known for its ability to support collagen and glycosaminoglycan synthesis. This helps improve skin thickness, elasticity, and overall lip structure. The key difference? DropPet® LipS Hot contains an additional natural thermal agent—Vanillyl Butyl Ether—which provides a gentle warming sensation upon application. This not only enhances the feeling of instant fullness but also promotes blood circulation, offering a soothing and pleasurable experience. Key Benefits: Lip Plumping: Reduces the appearance of fine lines and enhances lip volume. Fades Cheilogramma: Helps lighten dark or pigmented lips. Improves Lip Texture: Leaves lips softer, smoother, and more supple. Instant & Long-Term Results: LipS Hot offers immediate warmth and fullness, while both products support long-term lip rejuvenation. Backed by Science In vivo studies demonstrate that regular use of a lip balm containing DropPet® LipS (0.1%) significantly improves lip shape, softness, and protection. Volunteers reported: 100% improvement in lip shape 80% increase in lip softness 70% better lip protection Additionally, in vitro studies confirm that Palmitoyl Tripeptide-1 helps prevent collagen degradation caused by UVA exposure, supporting skin structure and resilience. Easy to Formulate These ingredients are oil-soluble and easily incorporated into: Lip balms Lip creams Lip masks Other lip care products Recommended Usage: 0.5%–5.0%Best Added: At 70–80°C during the final stages of production. Available Variants Both LipS and LipS Hot are available in two peptide concentrations: 0.1% and 0.01%, giving formulators flexibility based on desired potency and cost. Storage & Shelf Life Store in a dark place at room temperature (2–8°C recommended). Shelf life: 2 years. Whether you’re developing a luxury lip treatment or an everyday lip enhancer, DropPet® LipS and LipS Hot offer scientifically proven, customizable solutions for today’s beauty market. Interested in formulating with DropPet® LipS or LipS Hot?Contact us today for samples, technical data, or custom product options! If you are interested in our products and want to know more details, please contact judyzhou@drop-bio.com.    
  • Unlock Youthful Skin with DropPet® ElaS: A Multi-Peptide Powerhouse for Advanced Skincare Sep 18, 2025
    In the quest for ageless, radiant skin, the power of peptides has taken the cosmetic world by storm. Introducing DropPet® ElaS—a premium, multi-active peptide complex designed to comprehensively repair, rejuvenate, and protect the skin. Whether you're a formulator seeking a high-performance ingredient or a brand aiming to elevate your anti-aging range, DropPet® ElaS offers a scientifically advanced solution. What is DropPet® ElaS? DropPet® ElaS is a sophisticated blend of high-activity peptides including: Tripeptide-1 Hexapeptide-9 Palmitoyl Tripeptide-1 Palmitoyl Tripeptide-5 Palmitoyl Tetrapeptide-7 Palmitoyl Pentapeptide-4 This synergistic combination works through multiple pathways to revitalize skin structure, enhance elasticity, and reduce visible signs of aging. Key Benefits at a Glance ✅ Stimulates collagen, elastin, and glycosaminoglycan synthesis ✅ Repairs the epidermal barrier and basal membrane ✅ Enhances skin regeneration and keratin production ✅ Improves skin texture, firmness, and softness ✅ Reduces wrinkles and fine lines ✅ Offers long-term anti-aging effects How Does DropPet® ElaS Work? Aging, UV exposure, and environmental pollution degrade skin structure—thinning the epidermis, fragmenting collagen, and impairing the dermal-epidermal junction. DropPet® ElaS counteracts these effects through its multi-target mechanism: Hexapeptide-9 and Tripeptide-1 promote rapid epidermal regeneration and strengthen the basal membrane. Palmitoyl Pentapeptide-4 (also known as “micro-collagen”) penetrates deeply to stimulate fibroblasts, boosting production of Types I, III, and IV collagen and hyaluronic acid. Palmitoyl Tetrapeptide-7 reduces inflammation by inhibiting IL-6 release—outperforming even DHEA in clinical models. Palmitoyl Tripeptide-1 and Palmitoyl Tripeptide-5 activate TGF-β, enhancing collagen and glucosamine synthesis for improved skin density and elasticity. Application & Usage Recommended Inclusion: 0.1% – 5% Ideal For: Anti-aging serums, creams, lotions, eye treatments, and restorative skincare products Storage: Keep refrigerated at 2–8°C; protect from light Shelf Life: 24 months Packaging: 1kg / 10kg or custom options available Why Choose DropPet® ElaS? This innovative ingredient doesn’t just target one aspect of aging—it offers a holistic approach by: Repairing both epidermal and dermal layers Supporting ECM (extracellular matrix) remodeling Providing anti-inflammatory and regenerative benefits Delivering clinically-inspired results suitable for professional and consumer markets Perfect For: Anti-wrinkle and firming formulations Products targeting sagging skin and loss of elasticity Post-treatment and regenerative skincare lines Daily use products aimed at preventing premature aging Formulate with Confidence Backed by research and developed for efficacy, DropPet® ElaS is your go-to ingredient for creating cutting-edge skincare that truly performs. Elevate your formulations with this powerful peptide complex and help your customers reveal smoother, firmer, and more youthful-looking skin. Interested in incorporating DropPet® ElaS into your next product?Contact us today for technical data, samples, and formulation support. If you are interested in our products and want to know more details, please contact judyzhou@drop-bio.com.  
  • Unlock Radiant Skin with DropCare® CP: The Ultimate Hydrolyzed Collagen for Skincare Sep 10, 2025
    In the ever-evolving world of cosmetics, finding an ingredient that delivers multiple benefits while being safe and effective is like discovering gold. Meet DropCare® CP – a premium Hydrolyzed Collagen that’s transforming skincare formulations worldwide. What is DropCare® CP? DropCare® CP is a high-purity hydrolyzed collagen derived through advanced hydrolysis, resulting in a product with a protein content of over 92%. It is rich in 18 amino acids and essential trace elements, with particularly high levels of alanine, glycine, proline, and hydroxyproline – all crucial for maintaining skin health and vitality. Key Benefits at a Glance ✅ Deep Moisturization – Enhances skin hydration and softness. ✅ Powerful Antioxidant – Fights free radicals to prevent premature aging. ✅ Repairs Photo-Damage – Helps reverse signs of sun-induced skin aging. Why Choose Hydrolyzed Collagen? Collagen is a fundamental building block of the skin. It provides structure, elasticity, and strength. However, as we age, collagen production declines, leading to wrinkles, sagging, and loss of firmness. DropCare® CP features a low molecular weight, allowing for better skin absorption. It supplies the necessary amino acids to boost collagen synthesis, reduce wrinkles, and promote a more youthful complexion. Proven Antioxidant Properties DropCare® CP isn’t just a moisturizer – it’s a potent antioxidant: Scavenges OH and DPPH Free Radicals:Studies show that hydrolyzed collagen effectively neutralizes harmful free radicals. At concentrations of 20–40 mg/mL, its free-radical scavenging ability is comparable to that of Vitamin C. Inhibits Lipid Peroxidation:By reducing Malondialdehyde (MDA) levels – a marker of oxidative stress – DropCare® CP helps protect skin integrity and delay aging. Fights Photoaging & Repairs Sun Damage Exposure to UV radiation is a leading cause of skin aging. DropCare® CP has been tested in photoaging models and demonstrated significant protective effects: Reduces skin roughness, wrinkles, and pigmentation Restores skin elasticity and thickness Stimulates fibroblast activity and collagen production In fact, high-dose applications showed results similar to those of Vitamin C, making it an excellent anti-aging agent in sun care and rejuvenation products. Application & Safety Recommended Dosage: 0.01% – 10.0% Solubility: Water-soluble – easily incorporated into serums, creams, masks, and lotions Safety: Recognized as safe by US FDA and European regulatory bodies Storage: Store at room temperature, away from light, in a sealed container Shelf Life: 2 years Technical Specifications     Parameter Specification Appearance White to off-white powder Protein Content ≥90% Peptides <10,000 Da ≥92% Hydroxyproline ≥3.0% Heavy Metals ≤2.0 ppm Microbial Count Within safe limits Ideal For Anti-aging creams & serums Hydrating masks & moisturizers Sun repair & after-sun products Nutricosmetics & functional skincare Conclusion DropCare® CP (Hydrolyzed Collagen) is more than just a trend – it’s a scientifically backed, multifunctional ingredient that addresses hydration, oxidation, and photo-damage all at once. Whether you’re developing a new line or upgrading an existing product, DropCare® CP offers a safe, effective, and premium solution for modern skincare needs. Formulate with Confidence. Formulate with DropCare® CP. If you are interested in our products and want to know more details, please contact judyzhou@drop-bio.com.
  • Unlock Radiant Skin with DropCare® SRF: A Multi-Benefit Natural Ferment Ingredient Sep 08, 2025
    In the evolving world of skincare, natural and fermented ingredients continue to gain attention for their gentle yet effective properties. DropCare® SRF (Saccharomyces/Rice Ferment Filtrate) is one such innovative ingredient that stands out for its remarkable skin benefits. Sourced from rice fermented with yeast, this powerful filtrate is rich in sugars, organic acids, amino acids, and other bioactive compounds that promote healthier, brighter, and more hydrated skin. 🔬 What is DropCare® SRF? DropCare® SRF is a carefully formulated ingredient containing: Saccharomyces/Rice Ferment Filtrate Water Trehalose Xanthan Gum Hydroxyacetophenone 1,2-Hexanediol This blend is designed to support skin barrier function, enhance brightness, and provide long-lasting hydration. It is recommended for use at concentrations between 0.5% to 20% in various cosmetic formulations. 🌿 Key Benefits & Scientific Evidence 1. Reinforces Skin Barrier The skin’s barrier function relies heavily on proteins like Claudin-1, Claudin-4, and Occludin, which form tight junctions between cells. Studies have shown that DropCare® SRF significantly upregulates the expression of these proteins, strengthening the skin barrier without promoting cell proliferation. This effect is comparable to that induced by high calcium ion concentration, a known booster of tight junction formation. Reference: Yang et al. (2022). Study on Upregulation of Tight Junction Proteins and Enhancement of Skin Barrier Effect by Rice Ferment Filtrate. 2. Brightening & Whitening Clinical tests involving human volunteers demonstrated that formulations containing DropCare® SRF led to a noticeable increase in skin luminance (L* value) and Individual Typology Angle (ITA° value). Results were statistically significant after just one week of use, with continued improvement over four weeks. The brightening effect was clearly distinguishable from the base formula, confirming the efficacy of the rice ferment filtrate. Reference: Lei et al. (2020). Study on the Skin Whitening and Moisturizing Effects of Rice Ferment Filtrate. 3. Intense Hydration DropCare® SRF also excels in boosting skin moisture levels. Measured via skin moisture content (MMV), the ingredient showed a positive trend throughout the four-week trial, outperforming the base group. By the fourth week, the difference was significant, proving its ability to enhance skin hydration effectively. Reference: Cao et al. (2020). Research on the Skin Moisturizing Efficacy of Rice Ferment Filtrate. 📦 Specifications & Storage Appearance: Light yellow transparent liquid Odor: Characteristic pH: 5.0–7.0 Density: 0.950–1.060 Solid Content: ≥ 5.0% Microbial Limits: Total Plate Count: ≤ 100 CFU/mL Yeast & Mold: ≤ 10 CFU/mL Heavy Metals: Lead (Pb): ≤ 10 ppm Arsenic (As): ≤ 1.0 ppm Mercury (Hg): ≤ 0.1 ppm Packaging: 1 kg / 25 kgShelf Life: 2 yearsStorage: Store in a cool, dark place. Recommended temperature: 2–8°C. 💡 Application Ideas DropCare® SRF is ideal for a wide range of skincare products, including: Toners and essences Serums and ampoules Moisturizers and creams Barrier repair formulations Brightening treatments 🌾 Embrace Natural Efficacy With strong scientific backing and a natural origin, DropCare® SRF is an excellent choice for brands looking to develop effective, safe, and consumer-friendly skincare products. Whether you’re formulating for barrier support, whitening, or hydration—this ingredient delivers visible results. Interested in formulating with DropCare® SRF? Contact us for samples and technical documentation. If you are interested in our products and want to know more details, please contact judyzhou@drop-bio.com.
  • Unlock the Power of Nature with DropBrigt® Phlor: The Ultimate Multi-Functional Cosmetic Ingredient Aug 29, 2025
    In the ever-evolving world of skincare, consumers are increasingly seeking natural, effective, and safe ingredients. Meet DropBrigt® Phlor—a powerful plant-derived active that is revolutionizing cosmetic formulations with its exceptional multi-functional benefits. What is Phloretin? Phloretin is a natural dihydrochalcone flavonoid predominantly found in the peel and root bark of apples, pears, and other succulent fruits, as well as in plants like sweet tea and crabapple. Known for its strong antioxidant properties, phloretin has become a star ingredient in both cosmetics and functional foods. INCI Name: Phloretin CAS No.: 60-82-8 Molecular Formula: C₁₅H₁₄O₅ Key Benefits in Cosmetics 🌟 Skin Brightening & Whitening Phloretin effectively inhibits melanocyte activity and reduces the appearance of skin pigmentation and spots. Studies show that it outperforms well-known brightening agents like kojic acid and arbutin in tyrosinase inhibition. When combined with these agents, phloretin can achieve up to 100% inhibition—without the side effects. ✨ Antioxidant & Anti-Aging With an antioxidant capacity of 10.30 mg/L for lipid oxidation, phloretin neutralizes free radicals such as DPPH and ABTS, protects mitochondrial integrity, and delays skin aging. It helps maintain skin youthfulness and resilience against environmental stressors. 🔁 Anti-Inflammatory & Acne Care Phloretin soothes inflamed skin by blocking sugar penetration into epidermal cells, regulating sebum production, reducing COX-2 promoter activity, and inhibiting prostaglandin E2 synthesis. This makes it ideal for acne treatments and sensitive skin formulations. 💧 Transdermal Enhancement A safe and effective penetration enhancer, phloretin improves the absorption of other functional ingredients within cosmetic formulations, maximizing their efficacy—e.g., it significantly boosts the percutaneous absorption of Lidocaine HCl. 💆 Hair Loss Prevention By inhibiting soybean lipoxygenase (LOX), phloretin helps prevent premature hair aging and loss, making it a valuable addition to hair care products. Applications in Cosmetics Phloretin is widely used in a variety of skincare products, including: Whitening creams Repair serums Essences and toners Anti-aging treatments Acne solutions and soothing products Hair growth serums Leading global brands like SkinCeuticals have already incorporated phloretin into their bestselling products, recognizing its potent efficacy and consumer appeal. Safety & Regulations Phloretin is not only highly effective but also extremely safe: Oral LD₅₀: 5.760 g/kg (very low toxicity) Approved for use in cosmetics under China cosmetic ingredient code 02548 Complies with food additive standards (GB 1886.261-2016, GB2760 #N376) Recognized as GRAS by FEMA (#A390) and JECFA (#2022) Technical Specifications Indicator Specification Appearance Pearly white to light pink/yellow powder Odor Characteristic Assay ≥95.0% Melting Point 260–262°C Heavy Metals (Pb) ≤10 ppm Total Plate Count <1000 CFU/g Beyond Cosmetics: Food & Flavor Applications Phloretin also serves as a natural flavor modifier—especially useful in sugar-free or low-sugar food and beverage products. It masks bitterness, reduces off-notes from high-intensity sweeteners, and improves overall taste perception, often used in combination with stevia. Conclusion DropBrigt® Phlor is a versatile, evidence-based, and naturally derived active ingredient that meets the growing demand for safe and multifunctional components in cosmetics. Whether you’re developing serums, creams, toners, or haircare products, phloretin offers a compelling blend of efficacy, safety, and consumer trust. Enhance your formulations with DropBrigt® Phlor—where nature meets science. If you are interested in our products and want to know more details, please contact judyzhou@drop-bio.com.
  • Unlock Radiant Skin with DropBrigt® HPR P and DropBrigt® HPR L: The Next Generation of Retinoids Aug 22, 2025
    In the world of skincare, retinoids have long been celebrated for their remarkable ability to address a multitude of skin concerns—from aging and hyperpigmentation to acne. However, traditional retinoids like retinol often come with drawbacks such as instability, skin irritation, and sensitivity to light. Enter DropBrigt® HPR P and DropBrigt® HPR L—innovative, cosmetic-grade esters of all-trans retinoic acid (ATRA) that deliver potent results without the typical side effects. What Are DropBrigt® HPR P and HPR L? DropBrigt® HPR P (INCI: Hydroxypinacolone Retinoate) is a highly stable, direct-acting retinoid ester that combines retinoic acid with pinacol. Its unique structure allows it to bind directly to retinoid receptors in the skin without requiring metabolic conversion. This means faster, more efficient action with minimal irritation. DropBrigt® HPR L is a ready-to-use solution of Hydroxypinacolone Retinoate dissolved in Dimethyl Isosorbide (DMI), enhancing solubility and ease of formulation in serums, emulsions, and anhydrous systems. Key Benefits & Advantages: ✅ Direct Action: Unlike retinol or retinyl esters, which must convert into retinoic acid to become active, HPR works directly—no conversion needed.✅ Superior Stability: Excellent thermal and photochemical stability compared to traditional retinoids.✅ Low Irritation: Gentle enough for sensitive skin, with no significant phototoxicity or inflammatory response.✅ Enhanced Penetration: Smaller molecular size allows for better skin absorption.✅ Multi-Functional: Effectively targets aging, hyperpigmentation, acne, and skin barrier health. Supported by Science: Studies show that HPR significantly boosts procollagen production—on par with ATRA—while outperforming retinol, retinaldehyde, and retinyl palmitate in gene transcription activity. It also demonstrates remarkable skin tolerance and no phototoxicity, making it ideal for daily use. Ideal For: Anti-aging formulations Brightening and spot-correcting products Acne and blemish treatments Barrier repair and rejuvenating serums Day and night creams (compatible with “Vitamin C + A” routines) Usage Recommendations: DropBrigt® HPR P: Recommended dosage 0.01–0.2% DropBrigt® HPR L: Recommended dosage 0.1–2% Add to the oil phase before homogenization Store in light-protected packaging For best stability, combine with antioxidants or sunscreens Conclusion: DropBrigt® HPR P and HPR L represent a breakthrough in retinoid technology—offering unparalleled efficacy, stability, and gentleness. Whether you’re developing a revitalizing serum, an anti-aging cream, or an acne solution, these ingredients provide a powerful, customer-friendly option backed by cutting-edge science. Elevate your formulations with DropBrigt® HPR—where innovation meets skin transformation. If you are interested in our products and want to know more details, please contact judyzhou@drop-bio.com.
  • Unlock Youthful Radiance with DropBotatur® Algae S: Nature’s Answer to Sustainable Anti-Aging Aug 15, 2025
    Revolutionize Your FormulationsIntroducing DropBotatur® Algae S—a synergistic blend of Phyllacantha Fibrosa brown algae extract and Trifolium Pratense (red clover) extract. Backed by cutting-edge science and clinical proof, this innovative active ingredient delivers unparalleled anti-aging benefits while championing sustainability. Nature’s Powerhouse, Scientifically Enhanced Pure Oceanic Origins: Sourced from wild Ascophyllum nodosum (brown algae) in the pristine Pacific coastal waters of Chile and Peru. Harvested sustainably during low tide, its unique mucus—rich in bioactive compounds—is extracted using a patented, solvent-free process. Precision-Engineered Red Clover: Utilizes bud-stage whole-plant extract with cyclodextrin encapsulation to maximize bioavailability of key isoflavones (formononetin, biochanin A). Patented Technology for Superior Efficacy Molecular Weight Control: Patent ZL20171036972.5 employs microwave-assisted dissolution and ultrasonic degradation to achieve >70% of polysaccharides within 60–200 kDa. This optimizes antioxidant capacity and skin penetration. Key Actives: 30% Organic sulfated groups 20% Fucoidan 50% Mannitol, glucuronic acid & antioxidants Clinically Proven Anti-Aging Benefits In Vitro & Ex Vivo Results Boosts Structural Proteins: ↑ COL1 up to 35.24% | ↑ Elastin up to 63.91% (at 5% concentration) ↓ MMP-1 (collagen-degrading enzyme) by 28.40% Enhances Hydration & Firmness: ↑ Hyaluronic Acid by 114.52% | ↑ Collagen III by 69.26% Outperforms vitamin C in T-Skin™ model (+21.7% collagen vs. baseline). *28-Day Human Study (20 Volunteers, 35–65 y/o)* Brightening: ↑ ITA° (skin lightness) by 5.60 units (+7.8% vs. baseline). Firming: ↑ Skin Elasticity (F3/F4) to 0.91 (ideal = 1.0). Wrinkle Reduction: ↓ Skin Laxity (F4) by 110% after 56 days. Self-Assessment Scores (0–10): Parameter Day 56 Skin Brightness 9.15 Wrinkle Area Reduction 8.45 Skin Elasticity 6.25 Commitment to Safety & Sustainability Non-Irritating: HET-CAM test (ISI=4.53) confirms low irritation potential. Zero Residues: Pony Testing reports undetectable pesticides (<0.05 mg/kg). Eco-Conscious: Wild-harvested algae, pure water extraction, recyclable packaging. Application Guidelines Recommended Dose: 0.5–2% in creams, serums, and masks. Packaging: 1 kg/bottle or 25 kg/drum. Storage: 2-year shelf life at room temperature (avoid light). Formulate the Future, NaturallyDropBotatur® Algae S merges marine resilience with botanical intelligence to visibly firm, brighten, and rejuvenate skin. Ideal for clean, sustainable, and high-performance anti-aging products. If you are interested in our products and want to know more details, please contact judyzhou@drop-bio.com.  
  • DropBrigt® HEPES: The Multi-Tasking "Buffer-Plus" for Brighter, Smoother Skin Aug 07, 2025
    Unlock the hidden potential of formulations with DropBrigt® HEPES (INCI: Hydroxyethylpiperazine Ethane Sulfonic Acid, CAS 7365-45-9)—a bio-compatible buffer that transcends pH control to deliver exfoliation, brightening, and UV-protective synergy. Backed by cutting-edge 3D skin models, here’s why this versatile active belongs in your next brightening or anti-aging formula. 🌟 Triple-Action Benefits Gentle Exfoliation Weak acid (pH 4.5–6.5) with macromolecular AHA-like properties. Softens keratinocytes, smooths texture, and boosts cell turnover without irritation at recommended doses (0.5–5%). Clinical Brightening Power Proven Synergy: In 3D melanin skin models, formulations with HEPES + tranexamic acid + AA2G + niacinamide (Composition A): ↑ L* value (brightness) by 15% vs. controls (P<0.01) ↓ Melanin content by 30% (P<0.01) Outperformed fewer-actives combos (B/C) in reducing UV-induced pigmentation. UV Absorption & Penetration Boost Absorbs UVA/visible light, offering secondary photoprotection. Enhances delivery of co-actives (e.g., vitamin C, niacinamide). 🔬 Science Spotlight: Brightening Synergy Test Parameter Composition A Composition B Composition C Tranexamic Acid 3% – – AA2G 1% 1% – Niacinamide 2% 5% 6% HEPES 0.5% 0.5% 0.5% Result vs. UV-Damaged Skin ↑ L* value 15%↓ Melanin 30% Moderate improvement Minimal impact Key Insight: HEPES amplifies brightening efficacy in multi-active systems—0.5% HEPES doubled melanin reduction vs. niacinamide-only formulas. ⚙️ Formulator-Friendly Profile Solubility: Water-soluble (1M solution: clear, colorless). Stability: Heat/light-stable; pH 4–8 compatible. Addition: Flexible—cold or hot process (≤80°C). Safety: Mild irritation (IS=4.77 at 2% in chicken embryo test). Optimal use: 0.5–2% in leave-on products. ✅ Premium Quality Standards Parameter Specification Appearance White crystalline powder Purity (Assay) ≥99.5% Heavy Metals ≤10 ppm (Pb ≤2 ppm) Microbials Complies with ISO 11930 Shelf Life 2 years (room temp, sealed) 💡 Why Choose DropBrigt® HEPES? Beyond buffering, this "smart" active: Rescues UV-stressed skin via melanin suppression. Boosts actives’ efficacy in serums, toners, and creams. Works synergistically with brightening powerhouses (vitamin C, tranexamic acid). Simplifies formulating with water solubility and process flexibility. "HEPES isn’t just a pH adjuster—it’s a force multiplier for radiant skin results."   Elevate brightening formulations with DropBrigt® HEPES—where science meets synergy. If you are interested in our products and want to know more details, please contact judyzhou@drop-bio.com.
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