Unlock Next-Level Hydration: Meet DropCare® PGA70 & PGA01 – Your Smart Molecular Weight Choice
Jun 05, 2025
The PGA Revolution: One Ingredient, Two Powerful Profiles
In the quest for breakthrough hydrators, Polyglutamic Acid (PGA) has emerged as a game-changer. But not all PGAs are created equal. At DropBio®, we engineered DropCare® PGA70 (700 kDa) and DropCare® PGA01 (10 kDa) to deliver targeted performance across all cosmetic formulations. Here’s why molecular weight matters:
The Science Behind PGA
Sodium Polyglutamate is a natural, fermentation-derived polymer with a unique γ-peptide bond structure (linking α-amino and γ-carboxyl groups). Its secret lies in:
5000%+ water-binding capacity (outperforming hyaluronic acid)
Dense carboxyl side chains forming H-bond networks
Biofilm-forming ability that locks moisture into skin
Tailored Solutions: Molecular Weight Magic
Property
DropCare® PGA70 (700 kDa)
DropCare® PGA01 (10 kDa)
Primary Function
Surface Film-Former
Deep Skin Penetrator
Texture
Velvety-thick
Featherlight
Key Benefits
• 24H barrier-locking hydration• Wrinkle-smoothing film• Enhances product spreadability
• Boosts NMF synthesis• Transports actives deep into skin• Instant plumping effect
Best For
Creams/Masks/Leave-on products
Serums/Toners/Rinse-off formulas
Proven Efficacy: Beyond Basic Moisturization
Both variants deliver multi-mechanistic anti-aging results:✅ 3X Hyaluronic Acid Boost (in-vivo data)✅ 28% Reduction in TEWL after 4 weeks✅ 19% Improvement in skin elasticity✅ Melanin Inhibition for brightening
Why Formulators Choose DropCare®
▶ PGA70 (700 kDa) – The Shield
Creates breathable moisture-trapping mesh
Perfect for high-viscosity anti-aging creams
Use at 0.5-1.0% for cushion-like texture
▶ PGA01 (10 kDa) – The Spear
Penetrates stratum corneum in <30 sec
Ideal for watery essences & boosters
Effective at 0.1-0.5% with zero tackiness
Application Genius
Pair them for synergistic effects:
Cleanser: PGA01 (0.2%) → Preps skin for absorption
Toner: PGA01 (0.3%) + PGA70 (0.1%) → Multi-depth hydration
Cream: PGA70 (0.8%) → Seals in active ingredients
If you are interested in our products and want to know more details, please contact judyzhou@drop-bio.com.