In the world of skincare, retinoids have long been celebrated for their remarkable ability to address a multitude of skin concerns—from aging and hyperpigmentation to acne. However, traditional retinoids like retinol often come with drawbacks such as instability, skin irritation, and sensitivity to light. Enter DropBrigt® HPR P and DropBrigt® HPR L—innovative, cosmetic-grade esters of all-trans retinoic acid (ATRA) that deliver potent results without the typical side effects.
DropBrigt® HPR P (INCI: Hydroxypinacolone Retinoate) is a highly stable, direct-acting retinoid ester that combines retinoic acid with pinacol. Its unique structure allows it to bind directly to retinoid receptors in the skin without requiring metabolic conversion. This means faster, more efficient action with minimal irritation.
DropBrigt® HPR L is a ready-to-use solution of Hydroxypinacolone Retinoate dissolved in Dimethyl Isosorbide (DMI), enhancing solubility and ease of formulation in serums, emulsions, and anhydrous systems.
✅ Direct Action: Unlike retinol or retinyl esters, which must convert into retinoic acid to become active, HPR works directly—no conversion needed.
✅ Superior Stability: Excellent thermal and photochemical stability compared to traditional retinoids.
✅ Low Irritation: Gentle enough for sensitive skin, with no significant phototoxicity or inflammatory response.
✅ Enhanced Penetration: Smaller molecular size allows for better skin absorption.
✅ Multi-Functional: Effectively targets aging, hyperpigmentation, acne, and skin barrier health.
Studies show that HPR significantly boosts procollagen production—on par with ATRA—while outperforming retinol, retinaldehyde, and retinyl palmitate in gene transcription activity. It also demonstrates remarkable skin tolerance and no phototoxicity, making it ideal for daily use.
Anti-aging formulations
Brightening and spot-correcting products
Acne and blemish treatments
Barrier repair and rejuvenating serums
Day and night creams (compatible with “Vitamin C + A” routines)
DropBrigt® HPR P: Recommended dosage 0.01–0.2%
DropBrigt® HPR L: Recommended dosage 0.1–2%
Add to the oil phase before homogenization
Store in light-protected packaging
For best stability, combine with antioxidants or sunscreens
DropBrigt® HPR P and HPR L represent a breakthrough in retinoid technology—offering unparalleled efficacy, stability, and gentleness. Whether you’re developing a revitalizing serum, an anti-aging cream, or an acne solution, these ingredients provide a powerful, customer-friendly option backed by cutting-edge science.
Elevate your formulations with DropBrigt® HPR—where innovation meets skin transformation.
If you are interested in our products and want to know more details, please contact judyzhou@drop-bio.com.
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